NMN Clinical Trial Reveals Boost in NAD⁺ and Physical Performance in Just 60 Days
NMN Supplementation in Healthy Adults
Randomized, Placebo-Controlled, Dose‑Response Trial (2023)
🌟 What Customers Are Saying
⭐️⭐️⭐️⭐️⭐️ Alex Kirshbaum
“I’ve tried just about every supplement out there for energy and focus, but nothing compares to Nutra Needs NMN. Within the first week, I noticed a surge in strength during my morning workouts—and the best part is, that energy didn’t crash midday. I feel sharp, steady, and powerful from dawn to dusk. This is now a daily essential for me.”
⭐️⭐️⭐️⭐️⭐️ Wayne Tinsley
“This NMN is a total game-changer. I’m 52 and haven’t felt this strong in decades. My endurance at the gym has gone up noticeably, but what really stands out is how energized I feel throughout the day—no slumps, no fog, just clean, consistent energy. Nutra Needs nailed it with this formula.”
⭐️⭐️⭐️⭐️⭐️ Mark Layman
“I was skeptical at first, but wow—Nutra Needs NMN blew me away. After just a few days, I started waking up with more drive and pushing heavier weights at the gym. But it’s not just strength—it’s the all-day stamina that makes this product worth every penny. I feel like I gained back 10 years of energy.”
Lin Yi et al. “The efficacy and safety of β‑nicotinamide mononucleotide (NMN) supplementation in healthy middle‑aged adults…” GeroScience, Epub Dec 8, 2022; Publ Feb 2023.
PMID: 36482258
🔬 Study Design
- Randomized, multicenter, double‑blind, placebo‑controlled
- N = 80 healthy adults (middle-aged)
- Four oral dose groups: 0 mg (placebo), 300 mg, 600 mg, 900 mg/day
- Duration: 60 days
- Primary: blood NAD⁺ levels; Secondary: 6‑min walk test, SF-36 health survey, HOMA-IR, safety/tolerability
✅ Key Findings
- All NMN doses significantly increased blood NAD⁺ vs placebo by Days 30 & 60 (p≤0.001)
- 600 mg and 900 mg yielded the highest NAD⁺ levels
- Participants reported improved physical performance (6‑min walk) & general health (SF‑36)
- No serious adverse events—well tolerated across doses
🧠 Takeaway
Daily NMN supplementation (≥300 mg) safely and dose‑dependently boosted NAD⁺ and showed early signs of improved physical performance and general well‑being. This positions NMN as a promising NAD⁺ booster; further clinical trials (longer, diverse populations) are essential before mainstream therapeutic use.

